Full Conference Agenda

Home / Schedule / Full Conference Agenda

Abstract Details

<< Back to Detailed Agenda

10/09/2023  |   2:30 PM - 2:55 PM   |  6613

Establishing standardized case definitions for congenital cytomegalovirus (cCMV) infection and disease in the United States

Abstract Summary

A recent assessment of congenital cytomegalovirus (cCMV) activities found at least 10 U.S. state public health departments (HDs) were conducting cCMV surveillance by 2022, but were using various methods and inclusion criteria for case ascertainment, reporting, and classification. A workgroup (WG) of HDs and CMV experts was convened to write a position statement (PS) with the goal of creating standardized case definitions for cCMV infection and disease to be used for public health surveillance. This PS was submitted to the Council of State and Territorial Epidemiologists (CSTE) for consideration at their 2023 Annual Conference Business Meeting. Three case classifications are proposed based on laboratory and clinical criteria: confirmed cCMV infection, confirmed cCMV disease, and probable cCMV disease. Standard data sources and case ascertainment or reporting criteria that would trigger case investigations by HDs are also proposed. If approved by CSTE, use of the standardized case definitions may be voluntarily implemented by states beginning January 1, 2024. The WG is not recommending cCMV infection or disease be added to the list of nationally notifiable conditions. As states implement cCMV surveillance, standardized case definitions for cCMV infection and disease can be used to understand the epidemiology of cCMV and compare trends across the United States. Though these case definitions are not intended for clinical use, nationwide public health surveillance data obtained by using these standardized definitions will be useful to increase awareness of cCMV among healthcare providers and the public. Further, standardized case definitions and surveillance methods for cCMV infection and disease will be increasingly important to determine baseline cCMV prevalence as CMV vaccines get closer to licensure in the United States.

Learning Objectives

  • Describe the laboratory and clinical criteria for each of the three proposed cCMV case classifications.
  • Explain the process of drafting a CSTE standardized case definition position statement.
  • Summarize the reasons for inclusion and exclusion of various cCMV laboratory and clinical criteria for both reporting and case classification purposes.

Presentation

3440589_16096MaxSidesinger.pdf

Handouts

No handouts have been uploaded.

Presenters


Max Sidesinger | Primary Presenter

msidesinger@utah.gov;
Max Sidesinger, MPH, is the CMV data coordinator and an epidemiologist for Utah’s Early Hearing Detection and Intervention Program. He collects information on every CMV test completed on a child under 1 year of age in Utah, per the state Communicable Disease Rule, and works with providers and families to ensure CMV testing for children who fall under Utah's CMV Public Education and Testing Mandate. Max provides analyses for both CMV and EHDI related data.  He has collaborated with researchers at the University of Utah on multiple newborn hearing-related projects, with the CDC on a pilot surveillance project for cCMV, and with the CSTE on a position statement for standardized cCMV surveillance. Max received his BS in biology and Masters in public health from the University of Utah. His career interest is in using epidemiological methods to address public health needs.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Kristen Nichols Heitman | Co-Author

wwd6@cdc.gov;
Kelley Raines, MPH, is an epidemiologist with the Vaccine Preventable Diseases Branch in the CDC’s Division of Viral Diseases in Atlanta, GA. Her primary areas of work include the epidemiology and prevention of measles, rubella, and cytomegalovirus.

ASHA DISCLOSURE

Financial -

Nonfinancial -

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Kelley Raines | Co-Author

pvw2@cdc.gov;
Kelley Raines, MPH, is an epidemiologist with the Vaccine Preventable Diseases Branch in the CDC’s Division of Viral Diseases in Atlanta, GA. Her primary areas of work include the epidemiology and prevention of measles, rubella, and cytomegalovirus.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Ashrita Rau | Co-Author

tcy3@cdc.gov;
Ashrita Rau, MPH, is an epidemiologist with the Vaccine Preventable Diseases Branch in the CDC’s Division of Viral Diseases in Atlanta, GA. Her primary areas of work include the epidemiology and prevention of measles, rubella, and cytomegalovirus.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Jessica Leung | Co-Author

JLeung@cdc.gov;
Jessica Leung is an epidemiologist in the Division of Viral Diseases at the Centers for Disease Control and Prevention. She works on infectious disease surveillance, outbreak investigations, and research-related projects on viral vaccine-preventable diseases in the United States. Ms. Leung received her BA in Biochemistry and Molecular Biology from Dartmouth College and MPH in Epidemiology of Microbial Diseases from Yale University.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Tatiana Lanzieri | Co-Author

uyk4@cdc.gov;
Tatiana M. Lanzieri, M.D., M.P.H., is a medical epidemiologist with the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention. She has over 20 years of experience in infectious disease epidemiology, surveillance, and outbreak investigation.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial -


David Sugerman | Co-Author

ggi4@cdc.gov;
David Sugerman, M.D., M.P.H., is a medical epidemiologist and team lead with the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention. His team focused on measles, rubella, and CMV epidemiology.

ASHA DISCLOSURE

Financial -

Nonfinancial -

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Stephanie Browning McVicar | Co-Author

smcvicar@utah.gov;
Dr. Stephanie Browning McVicar is the Director of the Early Hearing Detection and Intervention Program, the Children’s Hearing Aid Program, and the Cytomegalovirus (CMV) Public Education & Testing Program at the Utah Department of Health & Human Services. Dr. McVicar is an audiologist with expertise in infants and pediatrics, an advocate for CMV testing in newborns, and passionate about the prevention of congenital CMV infection. She is originally from Western New York and has extensive experience and knowledge in Audiology and the management of health care programs.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial - No relevant financial relationship exists.


Jacinda Merrill | Co-Author

jamerrill@utah.gov;
Jacinda Merrill, MPH, CHES, is the CMV epidemiologist for the Utah Early Hearing Detection and Intervention Program. She abstracts data from electronic health records of children who have tested positive for CMV within the first year of age. Jacinda enters health data, including CMV test results, newborn hearing screening results, and other relevant data on cCMV cases into Utah’s CMV registry. She performs analysis on confirmed, probable, and suspect cCMV cases. Jacinda’s position is part of a pilot surveillance project for cCMV in collaboration with the CDC. She received her BS in Public Health with an emphasis in Health Promotion, along with a Masters in Public Health from Brigham Young University. Jacinda’s career interests include using best practices in data analysis and communicating that data in audience-appropriate ways to positively impact public health.

ASHA DISCLOSURE

Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.

AAA DISCLOSURE

Financial - No relevant financial relationship exists.