Abstract Details
10/09/2023 | 3:00 PM - 3:25 PM | 6613
Uncovering the iceberg: describing the epidemiology of congenital cytomegalovirus through universal newborn screening
Abstract Summary
Minnesota began universal newborn screening for congenital cytomegalovirus (cCMV) using dried blood spots on February 6, 2023; statewide surveillance for cCMV began at the same time. Nearly all (99%) of babies born in Minnesota undergo newborn blood spot screening, lending a uniquely complete population-based cohort to describe the epidemiology of cCMV in Minnesota. Electronic lab reporting of clinical CMV results and review of vital record data aid in ascertaining cases that may be missed by newborn screening. Well defined comparison groups for epidemiological analysis are possible because infection and disease status will be known on a cohort that is representative of the entire birth population in Minnesota. In this session, we will describe the epidemiology of cCMV in Minnesota after the implementation of universal newborn screening. We expect to analyze data from approximately seven months of screening, including an estimated 36,000 newborns and an expected 180 newborns with CMV detected in dried blood spots. We will describe the classification of cases (those with infection vs disease), including the application of a proposed standardized surveillance case definition, the demographics and geographic distribution of cases relative to the entire Minnesota birth population, and the morbidity and mortality (including deaths identified prior to newborn screen collection) of cases. We will present analyses to determine whether there are populations that are disproportionately burdened by cCMV. Finally, we will review findings that may lend valuable information to public health programs to target areas for prevention and education.
Learning Objectives
- Describe the epidemiology of cCMV in Minnesota
- Identify populations disproportionately burdened by cCMV
- Review findings that can be used to improve public health
Presentation
Handouts
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Presenters
Jenna Hullerman Umar | Co-Author
jenna.hullerman.umar@state.mn.us;
Jenna leads short term follow-up for several conditions screened using blood spot testing, including cCMV, at the Minnesota Department of Health. She serves as the main point of contacts for specialists throughout the state who serve families completing initial follow-up testing and diagnosis after an abnormal newborn screening result. Her educational background includes a Bachelor of Arts degree in Biological/Archaeological Anthropology, and a Master of Public Health in Maternal and Child Health Epidemiology. Outside of work, Jenna enjoys reading fantasy novels, nerding out with her family on home science projects, dancing, and learning about other cultures.
ASHA DISCLOSURE
Financial - No relevant financial relationship exists.
Nonfinancial - No relevant nonfinancial relationship exists.
AAA DISCLOSURE
Financial - No relevant financial relationship exists.
Lexie Barber | Co-Author
lexie.barber@state.mn.us;
Lexie Barber is an epidemiologist in the Longitudinal Follow-up unit at the Minnesota Department of Health (MDH) focusing on congenital CMV and heritable conditions. Lexie joined the team in December 2022. Previously, she worked in the infectious disease divisions at MDH and the North Dakota Department of Health working mainly in vaccine preventable diseases. Lexie received her Bachelor of Science in microbiology at North Dakota State University and her Master of Public Health in environmental health from the University of Minnesota.
ASHA DISCLOSURE
Financial - No relevant financial relationship exists.
Nonfinancial - No relevant nonfinancial relationship exists.
AAA DISCLOSURE
Financial - No relevant financial relationship exists.
Sondra Rosendahl | Co-Author
sondra.rosendahl@state.mn.us;
Sondra is a licensed genetic counselor who has been with the Minnesota Department of Health (MDH) Newborn Screening Program since 2011. Sondra is the coordinator of MDH’s Advisory Committee on Heritable and Congenital Disorders whose role is to provide advice and recommendations to the Minnesota Commissioner of Health concerning tests and treatments for disorders found in newborn children.
ASHA DISCLOSURE
Financial - Receives Grants for Other activities from Centers for Disease Control & Prevention.
Nonfinancial - No relevant nonfinancial relationship exists.
AAA DISCLOSURE
Financial - Receives support from Centers for Disease Control & Prevention for MDH has received a cooperative grant for laboratory surveillance: Epidemiology and Laboratory Capacity for Prevention and Control of Emerging Infectious Diseases.
Tory Kaye | Primary Presenter, Author
tory.kaye@state.mn.us;
Tory is an epidemiologist in the Newborn Screening Program at the Minnesota Department of Health. She leads epidemiology for the blood spot program, analyzing the program’s pre-analytical, analytical, and post-analytical dried blood spot data to improve the lives of babies in Minnesota. She received her Bachelors of Science degree in Animal Science and her Masters of Public Health degree both from the University of Minnesota. In her spare time, Tory enjoys camping and anything else involving the outdoors, as well as spending time with her family and friends including cat, 4 turtles,2 goats, and chickens.
ASHA DISCLOSURE
Financial - No relevant financial relationship exists.
Nonfinancial - No relevant nonfinancial relationship exists.
AAA DISCLOSURE
Financial - No relevant financial relationship exists.