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8/23/2022  |   2:15 PM - 2:40 PM   |  Governor General III

Update on the Status of Congenital Cytomegalovirus Surveillance in the United States

Despite high national prevalence (4.5 per 1,000 live births), congenital cytomegalovirus (cCMV) is not nationally notifiable in the United States, and a standardized case definition has not been established. To understand the status of cCMV state-based surveillance, CDC assessed surveillance activities through a review of state health department websites, an electronic survey, and interviews. Nine states made cCMV reportable to their birth defects registries (CO, IL, MI, OK, TX), newborn screening systems (CT, VA), or communicable disease systems (UT, DE). In these states, cCMV cases are ascertained from hospitals, providers, laboratories, vital records, and medical records, based on cCMV diagnostic codes (CO, MI, OK, TX), clinical diagnosis (IL), or laboratory confirmation (UT, CT, VA); however, limited data are collected. Four states (CO, OK, IL, TX) began surveillance efforts prior to the year 2000, but the remaining states (CT, VA, MI, UT) initiated surveillance activities within the last decade. This assessment found cCMV surveillance in a minority of states. As surveillance is more widely adopted and standardized, more data will be available to better understand the state-specific burden of cCMV and raise public awareness.

  • Describe the status of cCMV surveillance in the United States.
  • Summarize the different cCMV surveillance methods: case ascertainment, case definitions, data collection, data management, and follow-up requirements.
  • Compare cCMV surveillance case definitions.

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Session Evaluation


Kelley Raines (POC-Point of Contact,Primary Presenter), pvw2@cdc.gov;
Kelley Raines, MPH, is an epidemiologist with the Vaccine Preventable Diseases Branch in the CDC’s Division of Viral Diseases in Atlanta, GA. Her primary areas of work include the epidemiology and prevention of measles, rubella, and cytomegalovirus.

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