Abstract Details
8/23/2022 | 1:35 PM - 2:00 PM | Confederation II/III
Factors Associated with Congenital Cytomegalovirus Infection Detected by Dried Blood Spot Testing in
Children with congenital CMV (cCMV) have a high risk for unidentified and untreated hearing loss (HL), placing them at great risk for lasting impacts on quality of life and cognition. We sought to describe the factors associated with children with HL due to cCMV. We did a retrospective cohort study of pediatric patients who got CMV dried blood spot (DBS) testing in our HL clinic before April 1, 2022. Sociodemographic, audiologic, and medical variables were compared with CMV dried blood spot (DBS) results using odds ratios. Health of patients’ communities were based on Healthy Places Index (HPI) percentile scores. Of 365 children, 4% had a positive CMV DBS test. 53% were male, 58% were URM, 26% were non-English speakers, 55% had public insurance. The median HPI was 71.2 (range: 3.4-99.9). Those with asymmetric bilateral HL (OR 5.28, 95% CI 1.85-15.11) or profound HL (>90 dB) in either ear (OR 11.91, 95% CI 3.28-43.18) had higher odds of cCMV. Other sociodemographic (gender, race/ethnicity, language, insurance, HPI), medical, and audiologic variables (age at diagnosis, type and progression of HL) were not associated with cCMV. More research is warranted to identify cCMV children in a timely manner.
- Understand the sociodemographics of children with congenital cCMV.
- Understand the clinical characteristics of children with congenital CMV.
- Understand how to tailor clinical management for children with congenital CMV.
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Elizabeth Liao (POC-Point of Contact,Primary Presenter), elizabeth.liao@ucsf.edu;
Elizabeth Liao, BA, is a fourth-year medical student at the University of California, San Francisco who is planning to start her career in Otolaryngology – Head and Neck Surgery (OHNS). Currently at the Chan Lab, she is researching how care is delivered to children who are deaf and/or hard of hearing, in order to understand how we can better optimize their care. Looking forward, she hopes to create interventions in workflows and environments to improve healthcare delivery.
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ASHA DISCLOSURE: Financial - No relevant financial relationship exists. Nonfinancial - No relevant nonfinancial relationship exists. |
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AAA DISCLOSURE: Financial - Receives support from The Claire Giannini Fund for Grant. |