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8/22/2022  |   11:20 AM - 11:45 AM   |  Governor General II

Provider Testing Practices for Congenital Cytomegalovirus: Consistently Inconsistent

Background: Congenital cytomegalovirus (cCMV) is the leading non-genetic cause of sensorineural hearing loss and neurodevelopmental delays in children. Little is known about the medical decision-making and practices healthcare providers use to screen an infant for cCMV. Objective: To analyze healthcare provider practices used to screen infants for cCMV in a U.S. quaternary care pediatric hospital. Methods: An electronic medical record review was completed to identify all infants who underwent CMV testing over a five-year period (2014-2019). Infant demographics, clinical variables, testing indication by provider, screening modality and result were analyzed. Rate of true and missed diagnoses were calculated. Univariate and bivariate statistics were calculated. Results. During the five-year period, 25,609 infants were cared for at the study site. A total of 144 infants were tested for post-natal CMV and 41% (n=59) for cCMV by day of life 31. Among providers, those in the Neonatal Intensive Care Unit ordered the majority (40/59) of screens compared to those in the Newborn Nursery who ordered far less (7/59). Tested infants most frequently presented with jaundice/direct hyperbilirubinemia (n=38), thrombocytopenia (n=36), abnormal cran

  • To understand provider practices for testing for cCMV in a tertiary care center.
  • To discuss reasons why healthcare providers might not be testing for cCMV frequently.
  • To explore new systems level interventions could increase provider testing for cCMV.

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Session Evaluation

Kate Wilson (POC-Point of Contact,Primary Presenter), wkate@med.umich.edu;
Dr. Wilson is a pediatrician fellow in neonatology at the University of Michigan. Her research interests include understanding clinician practices around testing and screening for congenital cytomegalovirus in the neonatal period.


Financial - No relevant financial relationship exists.

Nonfinancial - No relevant nonfinancial relationship exists.


Financial - No relevant financial relationship exists.